Supplement Evidence Review
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Quietum Plus Review: Reading the Label Against the Guideline

By Supplement Evidence Review Editorial · First published 2026-08-24 · Last updated 2026-08-24 · 7 min read

Quietum Plus is sold for ringing in the ears. Its published supplement facts panel is dominated by red clover, black cohosh, dong quai, chaste tree and soy isoflavones — a combination that will look familiar to anyone who has shopped for menopause support. This review sets that panel against what the professional guideline for tinnitus actually says, and it is the most critical review in this series.

Our verdict

1.5/ 5 Not supported for its intended use

We cannot recommend this product, and it would be dishonest to soften that. The American Academy of Otolaryngology–Head and Neck Surgery Foundation's clinical practice guideline on tinnitus states directly: clinicians should not recommend ginkgo biloba, melatonin, zinc, or other dietary supplements for treating patients with persistent, bothersome tinnitus. That is the specialty's formal position on this entire product category.

Beyond that, the disclosed panel is a hormonal-support herbal blend. Red clover 400 mg, black cohosh 160 mg, dong quai 150 mg, chaste tree 100 mg, false unicorn and soy isoflavones are menopause formula staples, not auditory ingredients. Several carry real interaction and safety concerns. The point and a half it earns is for publishing an actual quantitative panel — which is more than several products in this series do. Tinnitus has treatments that genuinely help. They are further down this page.

Product type
Herbal capsule marketed for tinnitus and hearing support
Serving
2 capsules daily; 60 capsules per bottle
Largest ingredients
Red clover 400 mg, sage 200 mg, black cohosh 160 mg, dong quai 150 mg, licorice 150 mg
Also listed
Chaste tree 100 mg, false unicorn 50 mg, blessed thistle 50 mg, red raspberry 50 mg, soy isoflavones 30 mg, partridge berry 20 mg, Mexican yam 15 mg
Guideline position
AAO-HNSF: clinicians should not recommend dietary supplements for persistent tinnitus
Ingredients with tinnitus evidence
None on the panel
Notable interactions
Black cohosh (liver), dong quai (anticoagulants, pregnancy), licorice (blood pressure, potassium), soy isoflavones (hormone-sensitive conditions)
Typical price
Around $69 for one bottle, less per bottle in bundles
Guarantee
60-day money-back guarantee
Availability
Manufacturer's website only

What Quietum Plus is sold for

Quietum Plus is marketed to people with tinnitus — ringing, buzzing or hissing in the ears — and more broadly for "ear health" and hearing support. The sales narrative typically frames tinnitus as a problem of nerve health or inflammation that the right blend of herbs can address.

Tinnitus is a genuinely difficult condition. It affects a large share of adults, it can be distressing and sleep-destroying, and mainstream medicine has no pill that reliably silences it. That combination — high distress, real prevalence, no easy cure — is precisely the gap that supplement marketing fills. It is why this category exists, and why it deserves a careful review rather than an enthusiastic one.

What the label actually contains

To the manufacturer's credit, a quantitative panel is published. Here it is, with what each ingredient is conventionally used and studied for.

IngredientAmountTinnitus evidenceWhat it is conventionally used for
Red clover (aerial parts)400 mgNoneMenopausal hot flushes; isoflavone source
Sage (leaf)200 mgNoneHot flushes and night sweats; some cognitive research
Black cohosh (root)160 mgNoneMenopausal symptoms. Carries liver-safety signals
Dong quai (root)150 mgNoneTraditional women's health tonic
Licorice (root)150 mgNoneDigestive and adrenal traditional use
Chaste tree (fruit)100 mgNonePMS and cycle regulation; affects prolactin
False unicorn50 mgNoneTraditional female reproductive tonic. Endangered species concerns
Blessed thistle (herb)50 mgNoneTraditional digestive bitter; lactation support
Red raspberry (fruit)50 mgNoneTraditional pregnancy and uterine tonic
Soy isoflavones30 mgNonePhytoestrogens for menopausal symptoms
Partridge berry20 mgNoneTraditional women's tonic
Mexican yam (root)15 mgNoneMarketed for hormonal support; diosgenin source

Various marketing materials additionally mention maca, muira puama, epimedium, tribulus, ashwagandha, L-tyrosine, mucuna pruriens, damiana, catuaba, ginger, sarsaparilla and others without amounts. Where materials list ingredients that do not appear on the quantitative panel, the panel is the document that matters.

The mismatch between the panel and the purpose

Read the right-hand column of that table again. Red clover, black cohosh, dong quai, chaste tree, false unicorn, red raspberry, partridge berry, soy isoflavones, Mexican yam — this is, almost item for item, the composition of a conventional menopause and women's hormonal support formula. It is a coherent formula. It is simply a coherent formula for a different purpose.

Not one ingredient on the quantitative panel has clinical evidence for tinnitus

Not weak evidence. Not mixed evidence. We could not identify a single controlled human trial supporting any of these twelve ingredients as a treatment for tinnitus. The ingredients that have at least been studied for tinnitus — ginkgo biloba, zinc, melatonin — do not appear on the panel at all. And as the next section explains, even those failed.

There is a further wrinkle worth flagging for anyone considering this product. Several of these herbs are phytoestrogenic or otherwise hormonally active. Hormonal fluctuation is reported by some people to influence tinnitus perception, which might be the intended thread of logic. But an unproven, indirect hormonal mechanism is a thin basis for taking 400 mg of red clover and 30 mg of soy isoflavones daily — particularly for men, and particularly for anyone with a hormone-sensitive condition.

What the clinical guideline says

The American Academy of Otolaryngology–Head and Neck Surgery Foundation publishes the clinical practice guideline on tinnitus that ENT specialists in the United States work from. Its recommendation on this category is unusually blunt for a guideline document:

AAO-HNSF Clinical Practice Guideline: Tinnitus

"Clinicians should not recommend ginkgo biloba, melatonin, zinc, or other dietary supplements for treating patients with persistent, bothersome tinnitus."

Note the phrase "or other dietary supplements." The guideline is not merely saying three specific compounds failed. It is making a category-level recommendation, arrived at after reviewing the evidence, that supplements should not be recommended for this condition. Ginkgo — the most-studied supplement for tinnitus, with far more research behind it than anything in Quietum Plus — is named because it was tested properly and did not work.

A product whose ingredients have less tinnitus evidence than the ingredients the guideline explicitly tells clinicians not to recommend is not a close call.

Safety, interactions and who must avoid it

"Natural" is not "inert." This formula contains several herbs with documented pharmacological activity and real interaction risk at these doses.

  • Black cohosh (160 mg) — liver. Regulators in several countries have required liver-warning labelling following reports of hepatotoxicity. Causation is debated and cases are rare, but anyone with liver disease, or taking hepatotoxic medication, should avoid it. Stop immediately and seek care for jaundice, dark urine, upper abdominal pain or unusual fatigue.
  • Dong quai (150 mg) — bleeding and pregnancy. Contains coumarin derivatives; can potentiate warfarin and other anticoagulants and antiplatelets. It may stimulate uterine contractions and is contraindicated in pregnancy. It is also photosensitising.
  • Licorice (150 mg) — blood pressure and potassium. Glycyrrhizin can cause sodium retention, potassium loss and raised blood pressure with sustained use. Avoid with hypertension, heart failure, kidney disease, or with diuretics, digoxin or corticosteroids.
  • Red clover and soy isoflavones — hormone-sensitive conditions. Phytoestrogens. People with a history of breast, uterine or ovarian cancer, endometriosis or uterine fibroids should not take these without oncology or gynaecology advice, and they may interfere with tamoxifen.
  • Chaste tree affects prolactin and dopamine pathways; it can interact with dopamine agonists and antagonists, oral contraceptives and hormone therapy.
  • Blessed thistle and red raspberry — not for use in pregnancy without supervision.
  • Pregnancy and breastfeeding: avoid entirely. Several ingredients here are explicitly contraindicated in pregnancy.

The manufacturer's own materials acknowledge gastrointestinal effects, possible allergic reactions, black cohosh liver considerations and dong quai's pregnancy risk. That disclosure is to their credit — and it also confirms this is a pharmacologically active product that should not be taken casually.

Why delaying assessment matters

Some tinnitus needs urgent medical attention

See a doctor promptly — do not self-treat with supplements — if your tinnitus is in one ear only, is pulsatile (beating in time with your heart), came on suddenly, or is accompanied by sudden hearing loss, dizziness or vertigo, or facial weakness.

These patterns can indicate conditions including vestibular schwannoma, vascular abnormalities, Ménière's disease, or sudden sensorineural hearing loss — which is a medical emergency where steroid treatment within roughly two weeks substantially affects the chance of recovery. Weeks spent waiting for a supplement to work is exactly the window in which that opportunity is lost.

This is the core reason this review is as critical as it is. The financial cost of an ineffective supplement is recoverable. The cost of a delayed diagnosis sometimes is not.

What actually helps tinnitus

The absence of an effective pill does not mean nothing helps. These approaches have real evidence behind them, and most are accessible:

  • A proper audiological assessment first. Identify hearing loss, rule out the red flags above, and find any treatable cause. This is the step that matters most.
  • Hearing aids where there is hearing loss. Often the single most effective intervention — amplifying ambient sound reduces the contrast that makes tinnitus prominent.
  • Cognitive behavioural therapy. The best-evidenced intervention for tinnitus distress, and recommended in the guideline. It does not silence the sound; it substantially reduces how much the sound affects your life. Internet-delivered CBT programmes for tinnitus now exist and have trial support.
  • Sound therapy and masking — bedside noise generators, apps, or hearing aid masking features, particularly for sleep.
  • Reviewing your medications. A number of common drugs are ototoxic or can worsen tinnitus, including high-dose aspirin and NSAIDs, some antibiotics and loop diuretics. Ask a pharmacist to review your list.
  • Protecting your hearing from further noise exposure, and treating the sleep problems and anxiety that amplify tinnitus perception.

The American Tinnitus Association has written directly about the appeal of supplements in this space and why the evidence does not support them. It is worth reading before spending money on any product in this category.

Price, guarantee and refunds

Quietum Plus is sold direct-to-consumer at around $69 for a single bottle with lower per-bottle pricing on bundles, and a 60-day money-back guarantee. If you have already bought it and it has not helped, use that guarantee — keep your order number and follow the stated return process, and put the money toward an audiology appointment instead.

We are not placing a purchase link on this page. Recommending a product for a condition its own ingredient list has no evidence for, while a specialty guideline advises against the entire category, is not something a review with any credibility can do. If you want to buy it anyway, it is easy to find — but please read the safety section first, and please get your ears examined either way.

The bottom line

Quietum Plus publishes a real quantitative panel, which puts it ahead of several products in this series on transparency. That is the entirety of the good news.

The panel it publishes is a menopause-style herbal blend with no ingredient having clinical evidence for tinnitus, sold for a condition whose professional guideline explicitly advises against recommending dietary supplements. It contains herbs with genuine interaction risks — liver, bleeding, blood pressure and hormonal — that make it unsuitable for a lot of people who might buy it without knowing. And the most serious cost of using it is not the price but the delay, because some tinnitus is a symptom of something that needs treating quickly.

One and a half out of five. If tinnitus is affecting your life, spend the money on an audiologist and ask about CBT. That advice is worth considerably more than this product is.

Frequently asked questions

Does Quietum Plus work for tinnitus?

There is no clinical evidence that it does. No ingredient on its published supplement facts panel has controlled human trial evidence for tinnitus, and the AAO-HNSF clinical practice guideline states that clinicians should not recommend ginkgo biloba, melatonin, zinc, or other dietary supplements for persistent, bothersome tinnitus.

What is actually in Quietum Plus?

The published panel is dominated by red clover (400 mg), sage (200 mg), black cohosh (160 mg), dong quai (150 mg), licorice (150 mg) and chaste tree (100 mg), plus false unicorn, blessed thistle, red raspberry, soy isoflavones, partridge berry and Mexican yam. That combination is characteristic of menopause and women's hormonal support formulas rather than anything auditory.

Is it safe to take?

Not for everyone. Black cohosh carries liver-safety warnings; dong quai interacts with anticoagulants and is contraindicated in pregnancy; licorice can raise blood pressure and lower potassium; red clover and soy isoflavones are phytoestrogens that people with hormone-sensitive cancers, endometriosis or fibroids should avoid. Check with a pharmacist or doctor before taking it, especially alongside prescription medication.

Can men take it?

Nothing prevents it, but the formula is built from phytoestrogenic and traditionally female-reproductive herbs at meaningful doses. Given there is no tinnitus evidence for any of it, we see no reason for a man to take 400 mg of red clover and 30 mg of soy isoflavones daily.

When should I see a doctor about tinnitus instead?

Urgently if it is in one ear only, pulses in time with your heartbeat, started suddenly, or comes with sudden hearing loss, dizziness or facial weakness. Sudden sensorineural hearing loss is treatable with steroids but the window is roughly two weeks — delay costs recovery. Otherwise, still get an audiological assessment as your first step.

What helps tinnitus if supplements don't?

Hearing aids where there is hearing loss, cognitive behavioural therapy for the distress tinnitus causes, sound therapy and masking for sleep, reviewing ototoxic medications, protecting against further noise damage, and treating co-occurring anxiety and insomnia. CBT in particular has the strongest evidence base for improving quality of life.

Can I get a refund?

The stated policy is a 60-day money-back guarantee. If you have bought it and it has not helped, use it — keep your order confirmation and follow the return process on the manufacturer's site.

References

  1. American Academy of Otolaryngology–Head and Neck Surgery Foundation. Clinical Practice Guideline: Tinnitus — recommendation against ginkgo biloba, melatonin, zinc and other dietary supplements. AAO-HNS
  2. American Tinnitus Association. The Allure of the Magic Pill. ATA
  3. Quietum Plus published ingredients and side-effects document (manufacturer material), supplement facts panel as listed.
  4. National Center for Complementary and Integrative Health — monographs on black cohosh, dong quai, licorice root and red clover (safety and interaction profiles).
ED
Supplement Evidence Review Editorial We read the published supplement facts panel, then check each ingredient against human clinical research on PubMed and against professional-body guidance. We are not doctors and this page is not medical advice. Corrections: editor@example.com.